Clenbuterol UK: Clenbuterol for Sale, Buy Clenbuterol UK Online

What Is Clenbuterol?

Clenbuterol is known as a sympathomimetic amine, and it belongs to a class of drugs known as sympathomimetics. Other drugs in this classification include Caffeine, Albuterol, Ephedrine, and many others as it is a very broad category of drugs. All of these compounds (Caffeine, Albuterol, Ephedrine, Epinephrine, Norepinephrine, etc.) are very much ‘cousins’ of one another as they are all related with close similarities. The manner by which Clenbuterol works is by stimulating the sympathetic central nervous system in a variety of different pathways through different receptors known as adrenoreceptors that are located in all sorts of different tissues and cells in the body. Within the broad spectrum of the cells that these receptors are found in, Clenbuterol can act on these receptors and result in various different outcomes depending on which cell the receptors are found. The important thing to understand is that there are approximately 9 different adrenoreceptors found in the body, and are labeled as Alpha or Beta receptors with varying different numbers affixed to them (for example, Alpha-1, Alpha-2, Beta-1, Beta-2 receptors and so on and so forth). This is where the various different symathomimetic drugs differ from one another, in their receptor interaction. In Clenbuterol’s particular case, it is well known for targeting the Beta-2 receptors (effectively making Clenbuterol known as a B2 receptor agonist). The importance of this in regards to Clenbuterol’s fat burning advantages will be further explained later on. Clenbuterol has been shown to have a half-life of approximately 34 hours, making single daily doses a normal administering practice.

Common Uses for Clenbuterol

Although Clenbuterol in athletic, modeling, show business, and bodybuilding circles is primarily utilized as a fat loss agent, it was actually never originally utilized for this purpose in medicine. Many sympathomimetic drugs have been classified for use in treating a broad variety of conditions. In particular, Clenbuterol is widely used in asthma medications for those suffering from asthma. It can be commonly found as a main active ingredient in asthma inhalers for this purpose. This stems from the fact that Clenbuterol, when activating Beta-2 receptors in various tissues, enables bronchial dilation (opening of the airways) in the lungs and airways through the nose and throat. This is actually a well-known aspect of all sympathomimetic compounds (to varying degrees), including the body’s own neurotransmitters/hormones Epinephrine and Norepinephrine (Adrenaline and Noradrenaline respectively), by which drugs such as Clenbuterol have many similarities and actions. Other conditions which sympathomimetic compounds such as Clenbuterol are used for include: hypertension, cardiovascular shock/slowdown, arrhythmias, migraine headaches, allergic reactions and swelling, histamine reactions, and anaphylactic shock. Although Clenbuterol is a Beta-2 receptor agonist, it does have activity on other receptors in tissues, such as Beta-1 receptors for example, but this is to a very small extent. In comparison to Ephedrine, for example, Clenbuterol could be explained through the analogy that Clenbuterol’s action is akin to having several nails sticking out of a wooden surface where a hammer is used to hammer one specific nail on the head, but Ephedrine is the equivalent of using a larger sledgehammer to hit multiple nails on the head to drive them into the wood. Although not an exact analogy, this explains Clenbuterol’s activity fairly accurately

Clenbuterol’s Activity In Tissues

The use for Clenbuterol as a bronchodilator for asthma patients has been previously outlined, as well as the other clinical applications. However, what has not been yet explained (and what our main concern is) is its effect on fat metabolism. It is also known that Clenbuterol itself holds very mild anabolic effects on muscle tissue as well. Various animal studies have demonstrated Clenbuterol’s ability to have an anabolic effect on muscle tissue, although extremely mild and minor. The various studies that have been done, as well as the decades of anecdotal evidence from human bodybuilder users, demonstrate that this anabolic effect is quite negligible although it does exist. It would then behoove a user of Clenbuterol to understand that the use of this compound for purely its ‘anabolic’ effects would likely end up with disappointing results. It is therefore more important to regard Clenbuterol as a thermogenic fat loss agent first and foremost, and to treat it in this manner rather than an ‘anabolic’ agent (of which it is very poor at doing so). Evidence for this has been found in analysis of the studies done on animals whereby the animals were administered doses of Clenbuterol that were far above what the average human user would use for a cycle. This raises the common question as to whether Clenbuterol is actually anabolic at all in humans. With this being said, the Beta-2 agonist trait of Clenbuterol lends it some quite strong fat loss attributes. Through stimulating Beta-2 receptors on fat cells, Clenbuterol directly activates fat metabolism and begin the process of breaking down triglycerides into free fatty acids. It is well known that Beta-2 receptors on fat tissue play a very large role in fat loss, more so than other Beta and Alpha receptors on fat tissue. It is for this reason also that cattle are frequently administered Clenbuterol alongside anabolic steroid compounds in order to have the leanest possible beef or pork for slaughter and consumed as food. However, it is important for any potential user to understand that Clenbuterol may not result in effective fat loss for everyone. Some may be better responders in terms of fat metabolism from a compound such as Ephedrine (due to its better interaction with multiple receptor types) than with Clenbuterol. With that being said, it is well known that Clenbuterol should affect most people with significant fat loss effects – but non-responders (or poor responders) do exist.

Finally, one extremely important consequence to consider when it comes to Clenbuterol is the issue of Beta-2 receptor downregulation. Through prolonged daily use, Beta-2 receptors down regulate in response to the receptor stimulation from Clenbuterol itself. This results in a diminished fat loss effect that must be remedied by either time off from the drug, or the use of Ketotifen (this will be discussed later on). The diminished fat loss for most people seems to be reported to be around the 2nd week mark, whereby a 2 week break is the normal protocol in order to have receptor sites naturally up regulate themselves. The rumor of Benadryl (Diphenhydramine Hydrochloride) use for receptor up regulation is a false rumor, and it is not advised that one should go about this practice with the hopes of increasing fat loss from Clenbuterol. There is no harm in the use of Benadryl with Clenbuterol, but one would be wasting their time doing so and it is important to make it clear that the use of Benadryl for this purpose was found to be a baseless rumor, and an ineffective practice.
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